HitPredict

Interactor 1: KAPA (P06244)
cAMP-dependent protein kinase type 1 (PKA 1) (EC 2.7.11.11) (CDC25-suppressing protein kinase) (PK-25)
Gene: TPK1

Interactor 2: TCPA (P12612)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)
Gene: TCP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 397 Sc			1 559
+	Hs
		609652 KAPCG_HUMAN (44-397): 1.3e-148: 426: 41.81		TCPG_HUMAN (4-555): 0: 575: 29.53
+	Hs
		681738 AKT1_HUMAN (21-392): 1.15e-146: 426: 35.01		TCPG_HUMAN (4-555): 0: 575: 29.53
+	Hs
		573129 KAPCG_HUMAN (44-397): 1.3e-148: 426: 41.81		TCPA_HUMAN (9-556): 0: 569: 62.23
+	Hs
		573141 AKT1_HUMAN (21-392): 1.15e-146: 426: 35.01		TCPA_HUMAN (9-556): 0: 569: 62.23
+	Hs
		826928 KS6B2_HUMAN (43-397): 2.4e-140: 410: 36.07		TCPG_HUMAN (4-555): 0: 575: 29.53
+	Hs
		609692 KAPCG_HUMAN (44-397): 1.3e-148: 426: 41.81		TCPH_HUMAN (4-556): 0: 555: 31.78
+	Hs
		681999 AKT1_HUMAN (21-392): 1.15e-146: 426: 35.01		TCPH_HUMAN (4-556): 0: 555: 31.78
+	Hs
		573515 KS6B2_HUMAN (43-397): 2.4e-140: 410: 36.07		TCPA_HUMAN (9-556): 0: 569: 62.23
+	Dm
		520038 AKT1_DROME (60-397): 4.34e-146: 429: 35.63		TCPA_DROME (10-552): 0: 546: 62.25
+	Hs
		1306721 KS6B2_HUMAN (43-397): 2.4e-140: 410: 36.07		TCPH_HUMAN (4-556): 0: 555: 31.78
+	Hs
		568585 KAPCA_HUMAN (44-397): 2.33e-150: 430: 44.07		TCPE_HUMAN (17-552): 0: 530: 29.31
+	Hs
		609651 KAPCG_HUMAN (44-397): 1.3e-148: 426: 41.81		TCPE_HUMAN (17-552): 0: 530: 29.31
+	Hs
		681735 AKT1_HUMAN (21-392): 1.15e-146: 426: 35.01		TCPE_HUMAN (17-552): 0: 530: 29.31
+	Hs
		821449 KS6B2_HUMAN (43-397): 2.4e-140: 410: 36.07		TCPE_HUMAN (17-552): 0: 530: 29.31
+	Hs
		826897 SGK2_HUMAN (86-373): 7.93e-81: 254: 42.47		TCPG_HUMAN (4-555): 0: 575: 29.53
+	Hs
		573486 SGK2_HUMAN (86-373): 7.93e-81: 254: 42.47		TCPA_HUMAN (9-556): 0: 569: 62.23
+	Hs
		1306691 SGK2_HUMAN (86-373): 7.93e-81: 254: 42.47		TCPH_HUMAN (4-556): 0: 555: 31.78
+	Hs
		821419 SGK2_HUMAN (86-373): 7.93e-81: 254: 42.47		TCPE_HUMAN (17-552): 0: 530: 29.31
+	Dm
		1213398 AKT1_DROME (60-397): 4.34e-146: 429: 35.63		Q9VHL2_DROME (29-545): 1.85e-85: 276: 34.61
+	Dm
		1213438 AKT1_DROME (60-397): 4.34e-146: 429: 35.63		Q9W392_DROME (26-549): 8.14e-82: 267: 33.84