HitPredict

Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: ATF2 (P15336)
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (cAMP response element-binding protein CRE-BP1)
Gene: ATF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

The method score is based on:

Property	Details
Experiments	1641004, 11566021
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 4 others more... GO:0006355 - regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0097284 - hepatocyte apoptotic process
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	928
Hs

1	505

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024