HitPredict

Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: CCNE1 (P24864)
G1/S-specific cyclin-E1
Gene: CCNE1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.751

The method score is based on:

Property Details
Experiments 10499802, 10359664, 9053846, 8647086, 9885575, 9190208, 12676926, 9139732, 10486249
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 1 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 928
Hs

1 410
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024