HitPredict

Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

The method score is based on:

Property	Details
Experiments	10523633, 10376528, 16964284
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription and 2 others more... GO:0030308 - negative regulation of cell growth GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	928
Hs

1	272

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024