Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: HMGA2 (P52926)
High mobility group protein HMGI-C (High mobility group AT-hook protein 2)
Gene: HMGA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 0.60 0.578

The method score is based on:

Property Details
Experiments 16766265
Identification Methods affinity chromatography technology, pull down, far western blotting
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002062 - chondrocyte differentiation
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 928
Hs

1 109
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024