Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: PURA (Q00577)
Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)
Gene: PURA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 0.55 0.554

The method score is based on:

Property Details
Experiments 7592647
Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0050673 - epithelial cell proliferation
GO:0140297 - DNA-binding transcription factor binding
Homologous interactions 0

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Last updated: 15 Jul 2024