HitPredict

Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: CEBPE (Q15744)
CCAAT/enhancer-binding protein epsilon (C/EBP epsilon)
Gene: CEBPE

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	12947005
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 928 Hs			1 281
+	Hs
		414212 RB_HUMAN (1-928): 0: 1323: 100.00		CEBPA_HUMAN (1-281): 6.48e-49: 167: 33.33
+	Hs
		414159 RB_HUMAN (1-928): 0: 1323: 100.00		CEBPB_HUMAN (29-280): 1.52e-43: 153: 31.94
+	Hs
		414213 RB_HUMAN (1-928): 0: 1323: 100.00		CEBPD_HUMAN (2-277): 1.81e-42: 148: 34.01
+	Hs
		414152 RB_HUMAN (1-928): 0: 1323: 100.00		ATF2_HUMAN (53-267): 5.23e-28: 113: 18.42
+	Mm
		527139 RB_MOUSE (24-928): 0: 1260: 91.38		CEBPA_MOUSE (1-281): 2.29e-49: 168: 32.50
+	Mm
		527148 RB_MOUSE (24-928): 0: 1260: 91.38		CEBPD_MOUSE (3-280): 3.14e-47: 160: 33.11
+	Mm
		527132 RB_MOUSE (24-928): 0: 1260: 91.38		CEBPB_MOUSE (33-280): 1.14e-34: 128: 32.70
+	Rn
		645770 RB_RAT (1-928): 0: 1274: 88.90		CEBPG_RAT (191-281): 4.33e-26: 101: 41.76
+	Mm
		862832 RBL1_MOUSE (594-879): 2.53e-78: 278: 29.52		CEBPA_MOUSE (1-281): 2.29e-49: 168: 32.50