Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: LEF1 (Q9UJU2)
Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha)
Gene: LEF1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 24412244
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 928
Hs

1 399
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024