HitPredict

Interactor 1: PRGR (P06401)
Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)
Gene: PGR

Interactor 2: H90B2 (Q58FF8)
Putative heat shock protein HSP 90-beta 2 (Heat shock protein 90-beta b) (Heat shock protein 90Bb)
Gene: HSP90AB2P

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33846359
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 933 Hs			1 381
+	Hs
		377062 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		414418 PRGR_HUMAN (1-933): 3.14e-133: 424: 100.00		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		414416 PRGR_HUMAN (1-933): 3.14e-133: 424: 100.00		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		538337 ESR2_HUMAN (453-926): 9.09e-93: 305: 22.80		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		377287 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		TRAP1_HUMAN (135-380): 3.01e-42: 158: 20.45
+	Hs
		437625 MCR_HUMAN (12-933): 3.27e-105: 351: 29.16		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Mm
		415154 GCR_MOUSE (256-933): 1.73e-102: 339: 35.04		HS90B_MOUSE (109-251): 9.78e-33: 131: 86.71
+	Mm
		59437 A3KN90_MOUSE (12-933): 3.81e-99: 334: 29.91		HS90B_MOUSE (109-251): 9.78e-33: 131: 86.71
+	Hs
		431441 MCR_HUMAN (12-933): 3.27e-105: 351: 29.16		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		377022 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		437831 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Rn
		415133 GCR_RAT (256-933): 2.07e-97: 325: 34.31		HS90B_RAT (109-251): 9.78e-33: 131: 86.71
+	Hs
		377015 GCR_HUMAN (256-933): 3.11e-99: 330: 33.82		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		320158 ERR2_HUMAN (483-917): 5.66e-97: 313: 24.14		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		431458 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Rn
		415141 GCR_RAT (256-933): 2.07e-97: 325: 34.31		HS90A_RAT (87-251): 1.57e-26: 113: 59.41
+	Hs
		438124 NR1H3_HUMAN (473-916): 1.45e-95: 310: 20.97		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		320155 ERR2_HUMAN (483-917): 5.66e-97: 313: 24.14		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		431801 NR1H3_HUMAN (473-916): 1.45e-95: 310: 20.97		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		432122 ESR2_HUMAN (453-926): 9.09e-93: 305: 22.80		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54