HitPredict

Interactor 1: PRGR (P06401)
Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)
Gene: PGR

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33846359
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0051117 - ATPase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 933 Hs			1 456
+	Hs
		414530 PRGR_HUMAN (1-933): 3.14e-133: 424: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		487858 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		370743 ESR1_HUMAN (398-917): 2.19e-90: 301: 20.82		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		488037 RARA_HUMAN (480-915): 3.04e-84: 280: 17.66		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		487854 ANDR_HUMAN (122-933): 1.17e-97: 329: 29.70		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		1269957 ESR2_HUMAN (453-926): 9.09e-93: 305: 22.80		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		370738 ESR1_HUMAN (398-917): 2.19e-90: 301: 20.82		RUVB2_HUMAN (2-455): 0: 651: 42.76