Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35384245
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~fn3, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0016020 - membrane
GO:0043066 - negative regulation of apoptotic process
GO:0045471 - response to ethanol
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 297
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024