Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1
Interactor 2: CCNA2 (P20248)
Cyclin-A2 (Cyclin-A) (Cyclin A)
Gene: CCNA2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25852190, 33961781, 8423786, 32707033, 36736316, 21308745, 23602568, 19483727, 26186194, 26496610, 28514442, 12853968, 33422522, 17679094, 9053846, 8463339, 24302728, 1833185 |
| Identification Methods | affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cyclin_C~Pkinase, Cyclin_N~Pkinase |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0000086 - G2/M transition of mitotic cell cycle GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005654 - nucleoplasm and 6 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
