Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1
Interactor 2: PMYT1 (Q99640)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)
Gene: PKMYT1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.978 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9268380, 35271311, 32707033, 10373560, 25852190, 26186194, 28514442, 33961781, 23602568 |
| Identification Methods | enzymatic study, affinity chromatography technology, pull down, protein kinase assay, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | direct interaction, physical association, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0000086 - G2/M transition of mitotic cell cycle GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus and 7 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
