Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: MYLK2 (Q9H1R3)
Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18)
Gene: MYLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 32707033
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0010628 - positive regulation of gene expression
GO:0018107 - peptidyl-threonine phosphorylation
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 297
Hs

1 596
+ Hs
+ Hs
+ Hs
+ At
+ Mm
+ At
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024