HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16682949
Identification Methods	in-gel kinase assay
Interaction Type	phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0016020 - membrane GO:0016477 - cell migration GO:0051301 - cell division
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 335
+	Hs
		415055 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78
+	Hs
		960327 CDK5_HUMAN (1-293): 1.55e-134: 384: 56.12		NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78
+	Hs
		528401 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		MYH8_HUMAN (3-226): 2.41e-33: 132: 12.95
+	Hs
		625176 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		522542 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH1_HUMAN (3-226): 1.26e-35: 139: 13.84
+	Hs
		960129 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH13_HUMAN (3-243): 1.12e-35: 139: 12.03
+	Hs
		522604 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH7_HUMAN (3-226): 2.27e-35: 138: 12.95
+	Hs
		960128 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH2_HUMAN (3-226): 2.96e-35: 138: 14.29
+	Hs
		502908 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH3_HUMAN (3-235): 1.67e-33: 133: 12.88
+	Hs
		528405 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH8_HUMAN (3-226): 2.41e-33: 132: 12.95
+	Hs
		528368 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH6_HUMAN (3-226): 3.52e-33: 131: 13.39
+	Hs
		625177 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		MYH10_HUMAN (2-205): 2.43e-27: 115: 20.10