Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.696

The method score is based on:

Property Details
Experiments 28514442, 33306668, 33961781, 20581839
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006281 - DNA repair
GO:0007095 - mitotic G2 DNA damage checkpoint signaling
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 297
Hs

1 496
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ At
+ At
+ Hs
+ At
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024