HitPredict

Interactor 1: ATPB (P06576)
ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta)
Gene: ATP5F1B

Interactor 2: VATL (P27449)
V-type proton ATPase 16 kDa proteolipid subunit c (V-ATPase 16 kDa proteolipid subunit c) (Vacuolar proton pump 16 kDa proteolipid subunit c)
Gene: ATP6V0C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0070062 - extracellular exosome and 1 others more... GO:1902600 - proton transmembrane transport
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 529 Hs			1 155
+	Hs
		636810 ATPA_HUMAN (3-526): 1.12e-166: 485: 21.42		VATL_HUMAN (1-155): 2.12e-51: 162: 100.00
+	Hs
		597640 VATB2_HUMAN (13-499): 4.3e-167: 484: 23.11		VATL_HUMAN (1-155): 2.12e-51: 162: 100.00
+	Sc
		555927 VATB_YEAST (33-499): 2.71e-159: 465: 22.83		VATL2_YEAST (1-155): 2.36e-51: 162: 60.51
+	Hs
		547312 VATB1_HUMAN (46-499): 4.61e-159: 464: 23.86		VATL_HUMAN (1-155): 2.12e-51: 162: 100.00