Interactor 1: DED1 (P06634)
ATP-dependent RNA helicase DED1 (EC 3.6.4.13) (DEAD box protein 1) (Defines essential domain protein 1)
Gene: DED1

Interactor 2: IF4A (P10081)
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37)
Gene: TIF1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 32469309, 25013175, 27494274
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, Helicase_C~Helicase_C
Common GO terms GO:0003724 - RNA helicase activity
GO:0003743 - translation initiation factor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006413 - translational initiation
and 3 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 604
Sc

1 395
+ Hs
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Last updated: 15 Jul 2024