Interactor 1: DED1 (P06634)
ATP-dependent RNA helicase DED1 (EC 3.6.4.13) (DEAD box protein 1) (Defines essential domain protein 1)
Gene: DED1

Interactor 2: IF4F1 (P39935)
Eukaryotic initiation factor 4F subunit p150 (eIF-4F p150) (eIF4F p150) (Translation initiation factor 4(4)-F(6) subunit gamma(3) protein 1) (eIF4G1) (mRNA cap-binding protein complex subunit p150)
Gene: TIF4631

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 25013175, 27494274, 26777405, 31141444, 37968396, 21925384, 14759368, 16429126
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~MIF4G, Helicase_C~MIF4G
Common GO terms GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0005737 - cytoplasm
GO:0006413 - translational initiation
GO:0010494 - cytoplasmic stress granule
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 604
Sc

1 952
+ Sc
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024