HitPredict

Interactor 1: DED1 (P06634)
ATP-dependent RNA helicase DED1 (EC 3.6.4.13) (DEAD box protein 1) (Defines essential domain protein 1)
Gene: DED1

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	23332755, 19536198
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010494 - cytoplasmic stress granule GO:0016887 - ATP hydrolysis activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 604 Sc			1 613
+	Sc
		624216 DBP1_YEAST (1-604): 0: 541: 65.91		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		415872 DED1_YEAST (1-588): 0: 531: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		624104 DBP2_YEAST (31-600): 1.22e-148: 441: 37.98		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510336 DBP2_YEAST (31-600): 1.22e-148: 441: 37.98		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		133856 DDX3X_HUMAN (2-604): 2.32e-170: 501: 47.04		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		503397 DDX5_HUMAN (45-602): 9.94e-156: 462: 34.56		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		504506 DDX17_HUMAN (72-603): 3.65e-152: 456: 34.92		HSP7C_HUMAN (5-612): 0: 897: 60.00