HitPredict

Interactor 1: DED1 (P06634)
ATP-dependent RNA helicase DED1 (EC 3.6.4.13) (DEAD box protein 1) (Defines essential domain protein 1)
Gene: DED1

Interactor 2: BRE5 (P53741)
UBP3-associated protein BRE5 (Brefeldin-A sensitivity protein 5)
Gene: BRE5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	18467557, 20508643
Identification Methods	protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 604 Sc			1 515
+	Sc
		624140 DBP2_YEAST (31-600): 1.22e-148: 441: 37.98		BRE5_YEAST (1-515): 1.64e-126: 380: 100.00
+	Hs
		134017 DDX3X_HUMAN (2-604): 2.32e-170: 501: 47.04		G3BP1_HUMAN (4-495): 1.8e-78: 255: 15.74
+	Hs
		134250 DDX3X_HUMAN (2-604): 2.32e-170: 501: 47.04		G3BP2_HUMAN (4-492): 2.15e-75: 247: 14.14
+	Hs
		571431 DDX5_HUMAN (45-602): 9.94e-156: 462: 34.56		G3BP1_HUMAN (4-495): 1.8e-78: 255: 15.74