HitPredict

Interactor 1: AT1A2 (P06686)
Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(+) subunit) (Sodium pump subunit alpha-2)
Gene: Atp1a2

Interactor 2: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	32357304
Identification Methods	cross-linking study, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0043025 - neuronal cell body GO:0051087 - protein-folding chaperone binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1020 Rn			1 752
+	Rn
		416147 AT1A1_RAT (1-1020): 0: 1026: 86.22		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94112 AT1A1_RAT (1-1020): 0: 1026: 86.22		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Rn
		94113 AT1A2_RAT (1-1020): 0: 1023: 100.00		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Rn
		416169 AT1A3_RAT (26-1020): 0: 998: 88.35		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94114 AT1A3_RAT (26-1020): 0: 998: 88.35		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		496589 AT1A2_HUMAN (1-1020): 0: 1026: 99.12		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		392995 AT1A1_HUMAN (1-1020): 0: 1023: 86.41		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496196 AT1A3_HUMAN (24-1020): 0: 1000: 88.28		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Rn
		513722 AT2A2_RAT (40-1012): 0: 750: 26.27		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94131 AT2A2_RAT (40-1012): 0: 750: 26.27		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Mm
		223146 AT2A2_MOUSE (40-1011): 0: 751: 26.39		TAU_MOUSE (1-752): 1.92e-82: 279: 89.52
+	Hs
		496237 AT2A2_HUMAN (40-1012): 0: 750: 26.46		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		561576 AT2A2_HUMAN (40-1012): 0: 750: 26.46		MDC1_HUMAN (4-740): 1.03e-26: 119: 9.08