HitPredict

Interactor 1: SIR3 (P06701)
Regulatory protein SIR3 (Silent information regulator 3)
Gene: SIR3

Interactor 2: SIR3 (P06701)
Regulatory protein SIR3 (Silent information regulator 3)
Gene: SIR3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 11689698, 7958893, 15907466, 16717101, 31295433, 31366171, 18794362, 21896656, 23299941, 21179020
Identification Methods two hybrid, pull down, affinity chromatography technology, x-ray crystallography, tandem affinity purification, cosedimentation through density gradient, molecular sieving
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BAH~BAH
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0000792 - heterochromatin
GO:0003676 - nucleic acid binding
GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
and 16 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 978
Sc

1 978
+ Sc
+ Hs
+ Sc
+ Hs
+ Dm
+ Hs
+ Sc
+ Sp
+ Sp
+ Sp
+ Hs
+ Sp
+ Sp
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024