HitPredict

Interactor 1: SIR3 (P06701)
Regulatory protein SIR3 (Silent information regulator 3)
Gene: SIR3

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	26831523, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 978 Sc			1 463
+	Sc
		416334 SIR3_YEAST (1-978): 0: 937: 100.00		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Sc
		872798 ORC1_YEAST (1-975): 0: 754: 23.77		RUVB1_YEAST (1-463): 0: 682: 100.00
+	Sc
		872832 ORC1_YEAST (1-975): 0: 754: 23.77		RUVB2_YEAST (15-463): 0: 622: 41.15