HitPredict

Interactor 1: S10A9 (P06702)
Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9)
Gene: S100A9

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20936779
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030307 - positive regulation of cell growth GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 114 Hs			1 191
+	Hs
		416397 S10A9_HUMAN (1-114): 4.07e-47: 148: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		416345 S10A9_HUMAN (1-114): 4.07e-47: 148: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		380763 S100B_HUMAN (5-97): 2.99e-31: 107: 37.63		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		661224 S10A2_HUMAN (1-101): 2.02e-32: 110: 32.67		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		642929 S10A4_HUMAN (7-101): 5.27e-33: 112: 29.47		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		396714 S10A8_HUMAN (5-100): 3.01e-29: 102: 25.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		396675 S10A8_HUMAN (5-100): 3.01e-29: 102: 25.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		642957 S10A4_HUMAN (7-101): 5.27e-33: 112: 29.47		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82