HitPredict

Interactor 1: S10A6 (P06703)
Protein S100-A6 (Calcyclin) (Growth factor-inducible protein 2A9) (MLN 4) (Prolactin receptor-associated protein) (PRA) (S100 calcium-binding protein A6)
Gene: S100A6

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 90 Hs			1 758
+	Hs
		497264 HORN_HUMAN (1-86): 3.59e-30: 113: 28.41		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496312 S10A1_HUMAN (1-88): 9.49e-34: 112: 43.33		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		416341 S10A9_HUMAN (3-89): 8.47e-30: 103: 31.11		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496690 S10AA_HUMAN (1-88): 2.14e-29: 102: 26.67		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		380723 S100B_HUMAN (3-89): 1.01e-28: 100: 39.33		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497147 FILA2_HUMAN (3-88): 5.32e-25: 98.7: 31.82		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		396671 S10A8_HUMAN (1-89): 1.67e-27: 97.2: 25.84		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497487 S10AD_HUMAN (3-82): 2.72e-23: 86.8: 33.75		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497435 S10AG_HUMAN (3-89): 1.16e-21: 82.9: 27.78		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496287 FILA_HUMAN (1-86): 2.65e-19: 82.6: 31.82		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		152595 S10A2_HUMAN (1-90): 1.38e-31: 107: 45.65		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Bt
		361268 S100B_BOVIN (3-89): 2.97e-29: 101: 39.33		TAU_BOVIN (1-291): 3.66e-12: 71.3: 40.00