Interactor 1: DPO3X (P06710)
DNA polymerase III subunit tau (EC 2.7.7.7) (DNA polymerase III subunit gamma)
Gene: dnaX

Interactor 2: HOLB (P28631)
DNA polymerase III subunit delta' (EC 2.7.7.7)
Gene: HOLB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 11606586, 3283126, 7768937, 8505304, 11809766, 20223211, 15690043, 11463787, 11078742, 7494000
Identification Methods surface plasmon resonance, biochemical, molecular sieving, mass spectrometry studies of complexes, tandem affinity purification, pull down
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol3_delta2~DNA_pol3_delta2, DNA_pol3_delta2~DNA_pol3_gamma3, DNA_pol3_gamma3~DNApol3-delta_C
Common GO terms GO:0003677 - DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0006260 - DNA replication
GO:0006261 - DNA-templated DNA replication
GO:0009360 - DNA polymerase III complex
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 643
Ec

1 334
+ Ec
+ Tp
+ Bs
+ Hs
+ Hs
+ Hs
+ Bs
+ Hs
+ Hs
+ Mp
+ At
+ Dm
+ Dm
+ Dm
+ Zm
+ At

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Last updated: 15 Jul 2024