Interactor 1: CD2 (P06729)
T-cell surface antigen CD2 (Erythrocyte receptor) (LFA-2) (LFA-3 receptor) (Rosette receptor) (T-cell surface antigen T11/Leu-5) (CD antigen CD2)
Gene: CD2

Interactor 2: LFA3 (P19256)
Lymphocyte function-associated antigen 3 (Ag3) (Surface glycoprotein LFA-3) (CD antigen CD58)
Gene: CD58

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 0.55 0.592

The method score is based on:

Property Details
Experiments 11575926, 21982860
Identification Methods x-ray crystallography, pull down, protein array
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0032757 - positive regulation of interleukin-8 production
GO:0034113 - heterotypic cell-cell adhesion
and 1 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024