HitPredict

Interactor 1: IF4E (P06730)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: EIF4E

Interactor 2: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.621

The method score is based on:

Property Details
Experiments 29395067, 23665581
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010494 - cytoplasmic stress granule
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 217
Hs

1 636
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024