HitPredict

Interactor 1: IF4E (P06730)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: EIF4E

Interactor 2: DDX6 (P26196)
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
Gene: DDX6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	29395067, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 7 others more... GO:0010494 - cytoplasmic stress granule GO:0016442 - RISC complex GO:0017148 - negative regulation of translation GO:0019827 - stem cell population maintenance GO:0030182 - neuron differentiation GO:0036464 - cytoplasmic ribonucleoprotein granule GO:0045665 - negative regulation of neuron differentiation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	217
Hs

1	483

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024