Interactor 1: IF4E (P06730)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: EIF4E

Interactor 2: MKNK1 (Q9BUB5)
MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)
Gene: MKNK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.534

The method score is based on:

Property Details
Experiments 9878069
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006417 - regulation of translation
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 217
Hs

1 465
+ Mm
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024