HitPredict - High confidence protein-protein interactions

Interactor 1: CEAM5 (P06731)
Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e)
Gene: CEACAM5

Interactor 2: CEAM5 (P06731)
Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e)
Gene: CEACAM5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	26483485, 18086185
Identification Methods	cosedimentation in solution, x-ray crystallography, molecular sieving, surface plasmon resonance, cosedimentation through density gradient, comigration in sds page
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ig_2~Ig_2, Ig_2~Ig_3, Ig_2~V-set, Ig_3~Ig_3, Ig_3~V-set, V-set~V-set
Common GO terms	GO:0002682 - regulation of immune system process GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0006915 - apoptotic process GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules and 15 others more... GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007165 - signal transduction GO:0009986 - cell surface GO:0010832 - negative regulation of myotube differentiation GO:0016020 - membrane GO:0016323 - basolateral plasma membrane GO:0016324 - apical plasma membrane GO:0034109 - homotypic cell-cell adhesion GO:0034235 - GPI anchor binding GO:0042803 - protein homodimerization activity GO:0043066 - negative regulation of apoptotic process GO:0070062 - extracellular exosome GO:0098552 - side of membrane GO:1990782 - protein tyrosine kinase binding GO:2000811 - negative regulation of anoikis
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1	702
Hs

1	702

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Last updated: 15 Jul 2024