HitPredict

Interactor 1: KCRM (P06732)
Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK)
Gene: CKM

Interactor 2: KCRB (P12277)
Creatine kinase B-type (EC 2.7.3.2) (Brain creatine kinase) (B-CK) (Creatine kinase B chain) (Creatine phosphokinase B-type) (CPK-B)
Gene: CKB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 35235311
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-gua_Ptrans~ATP-gua_Ptrans, ATP-gua_Ptrans~ATP-gua_PtransN
Common GO terms GO:0004111 - creatine kinase activity
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0016310 - phosphorylation
and 1 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 381
Hs

1 381
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024