HitPredict

Interactor 1: KCRM (P06732)
Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK)
Gene: CKM

Interactor 2: KCRU (P12532)
Creatine kinase U-type, mitochondrial (EC 2.7.3.2) (Acidic-type mitochondrial creatine kinase) (Mia-CK) (Ubiquitous mitochondrial creatine kinase) (U-MtCK)
Gene: CKMT1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	32296183, 34349018, unassigned1304
Identification Methods	two hybrid, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ATP-gua_Ptrans~ATP-gua_Ptrans, ATP-gua_Ptrans~ATP-gua_PtransN
Common GO terms	GO:0004111 - creatine kinase activity GO:0005524 - ATP binding GO:0016310 - phosphorylation GO:0046314 - phosphocreatine biosynthetic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 417
+	Hs
		519114 KCRB_HUMAN (1-381): 0: 655: 80.58		KCRU_HUMAN (1-417): 0: 674: 100.00
+	Hs
		417069 KCRM_HUMAN (1-381): 0: 651: 100.00		KCRS_HUMAN (1-412): 0: 666: 80.15
+	Hs
		417066 KCRB_HUMAN (1-381): 0: 655: 80.58		KCRM_HUMAN (47-406): 0: 584: 67.59
+	Hs
		519748 KCRU_HUMAN (14-373): 0: 570: 67.59		KCRS_HUMAN (1-412): 0: 666: 80.15