HitPredict

Interactor 1: KCRM (P06732)
Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK)
Gene: CKM

Interactor 2: KCRS (P17540)
Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK)
Gene: CKMT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ATP-gua_Ptrans~ATP-gua_Ptrans, ATP-gua_Ptrans~ATP-gua_PtransN
Common GO terms	GO:0004111 - creatine kinase activity GO:0005524 - ATP binding GO:0016310 - phosphorylation GO:0046314 - phosphocreatine biosynthetic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 419
+	Hs
		519114 KCRB_HUMAN (1-381): 0: 655: 80.58		KCRU_HUMAN (1-413): 0: 637: 80.15
+	Hs
		417067 KCRM_HUMAN (1-381): 0: 651: 100.00		KCRU_HUMAN (1-413): 0: 637: 80.15
+	Hs
		519748 KCRU_HUMAN (14-373): 0: 570: 67.59		KCRS_HUMAN (1-419): 0: 710: 100.00
+	Hs
		417066 KCRB_HUMAN (1-381): 0: 655: 80.58		KCRM_HUMAN (48-407): 0: 587: 65.65