HitPredict

Interactor 1: ENOA (P06733)
Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein)
Gene: ENO1

Interactor 2: ENOG (P09104)
Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 2) (Neural enolase) (Neuron-specific enolase) (NSE)
Gene: ENO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 35235311, 34349018, 37071682, 36652389
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Enolase_C~Enolase_C, Enolase_C~Enolase_N, Enolase_N~Enolase_N
Common GO terms GO:0000015 - phosphopyruvate hydratase complex
GO:0000287 - magnesium ion binding
GO:0004634 - phosphopyruvate hydratase activity
GO:0005615 - extracellular space
GO:0005829 - cytosol
and 6 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 434
Hs

1 434
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc
+ Sc
+ Sc
+ Sa
+ Sp
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024