HitPredict

Interactor 1: MLC1 (P06742)
Myosin light chain alkali
Gene: MLC1

Interactor 2: MLR (P18432)
Myosin regulatory light chain 2 (MLC-2)
Gene: Mlc2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_6~EF-hand_7
Common GO terms	GO:0005509 - calcium ion binding GO:0032036 - myosin heavy chain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 155 Dm			1 222
+	Hs
		409446 MYL1_HUMAN (3-149): 1.74e-63: 194: 39.07		ML12A_HUMAN (61-219): 1.38e-68: 209: 40.37
+	Hs
		159559 MYL6_HUMAN (1-150): 2.98e-52: 164: 37.66		ML12B_HUMAN (60-219): 3.17e-69: 211: 40.12
+	Hs
		580632 MYL6_HUMAN (1-150): 2.98e-52: 164: 37.66		ML12A_HUMAN (61-219): 1.38e-68: 209: 40.37
+	Hs
		624346 MYL6_HUMAN (1-150): 2.98e-52: 164: 37.66		MYL9_HUMAN (61-219): 2.14e-68: 209: 39.13
+	Hs
		159536 MYL6B_HUMAN (3-149): 2.14e-44: 146: 36.42		ML12B_HUMAN (60-219): 3.17e-69: 211: 40.12
+	Hs
		538637 MYL6B_HUMAN (3-149): 2.14e-44: 146: 36.42		ML12A_HUMAN (61-219): 1.38e-68: 209: 40.37
+	Hs
		538639 MYL6B_HUMAN (3-149): 2.14e-44: 146: 36.42		MYL9_HUMAN (61-219): 2.14e-68: 209: 39.13
+	Hs
		409438 MYL1_HUMAN (3-149): 1.74e-63: 194: 39.07		CALM1_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	Hs
		409439 MYL1_HUMAN (3-149): 1.74e-63: 194: 39.07		CALM3_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	Hs
		483914 MYL6_HUMAN (1-150): 2.98e-52: 164: 37.66		CALM1_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	Hs
		483988 MYL6_HUMAN (1-150): 2.98e-52: 164: 37.66		CALM2_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	Hs
		484091 MYL6_HUMAN (1-150): 2.98e-52: 164: 37.66		CALM3_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	At
		188361 CML8_ARATH (4-149): 1.99e-51: 162: 27.70		CDPKU_ARATH (138-220): 5.68e-11: 63.1: 18.82
+	At
		188308 CML8_ARATH (4-149): 1.99e-51: 162: 27.70		CDPK3_ARATH (135-220): 1.09e-10: 62.3: 20.46
+	Hs
		484049 CALM3_HUMAN (2-149): 4.81e-46: 148: 27.33		CALM3_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	Hs
		483897 MYL6B_HUMAN (3-149): 2.14e-44: 146: 36.42		CALM1_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	Hs
		483970 MYL6B_HUMAN (3-149): 2.14e-44: 146: 36.42		CALM2_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	Hs
		484054 MYL6B_HUMAN (3-149): 2.14e-44: 146: 36.42		CALM3_HUMAN (15-139): 5.01e-15: 71.1: 17.56
+	Hs
		483903 CALM1_HUMAN (2-149): 4.81e-46: 148: 27.33		CALL3_HUMAN (140-220): 1.75e-09: 56.3: 21.69
+	Hs
		483976 CALM2_HUMAN (2-149): 4.81e-46: 148: 27.33		CALL3_HUMAN (140-220): 1.75e-09: 56.3: 21.69