Interactor 1: DPOLB (P06746)
DNA polymerase beta (EC 2.7.7.7) (5'-deoxyribose-phosphate lyase) (5'-dRP lyase) (EC 4.2.99.-) (AP lyase) (EC 4.2.99.18)
Gene: POLB
Interactor 2: XRCC1 (P18887)
DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)
Gene: XRCC1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 25423885, 28514442, 15520167, 29668892, 11467963, 33961781, 26496610, 15107487, 11909950, 8978692, 34111398, 15367657 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, far western blotting, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_pol_B_thumb~XRCC1_N |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006284 - base-excision repair GO:0006303 - double-strand break repair via nonhomologous end joining GO:0019899 - enzyme binding |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
