HitPredict

Interactor 1: DPOLB (P06746)
DNA polymerase beta (EC 2.7.7.7) (5'-deoxyribose-phosphate lyase) (5'-dRP lyase) (EC 4.2.99.-) (AP lyase) (EC 4.2.99.18)
Gene: POLB

Interactor 2: APTX (Q7Z2E3)
Aprataxin (EC 3.6.1.71) (EC 3.6.1.72) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT)
Gene: APTX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003684 - damaged DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 335 Hs			1 356
+	Hs
		417837 DPOLB_HUMAN (1-335): 3.98e-157: 444: 100.00		PNKP_HUMAN (20-155): 1.27e-57: 196: 34.31