Interactor 1: DPOLB (P06746)
DNA polymerase beta (EC 2.7.7.7) (5'-deoxyribose-phosphate lyase) (5'-dRP lyase) (EC 4.2.99.-) (AP lyase) (EC 4.2.99.18)
Gene: POLB

Interactor 2: APLF (Q8IW19)
Aprataxin and PNK-like factor (EC 3.1.-.-) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1)
Gene: APLF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.55 0.638

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0006303 - double-strand break repair via nonhomologous end joining
and 2 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024