HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: ZEP1 (P15822)
Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1)
Gene: HIVEP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 2718
+	Hs
		64134 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZN729_HUMAN (537-1014): 8.85e-43: 175: 8.32
+	Hs
		418468 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZFP62_HUMAN (1645-1998): 9e-31: 134: 8.33
+	Hs
		418242 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IKZF1_HUMAN (2001-2144): 1.33e-11: 71.9: 28.77
+	Hs
		418775 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IKZF3_HUMAN (358-457): 1.52e-11: 71.9: 35.00
+	Hs
		418401 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZN771_HUMAN (406-457): 4.46e-11: 68.8: 50.00
+	Hs
		64131 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZN729_HUMAN (537-1014): 8.85e-43: 175: 8.32
+	Hs
		271365 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZFP62_HUMAN (1645-1998): 9e-31: 134: 8.33
+	Hs
		196546 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZBT24_HUMAN (2008-2475): 6.03e-14: 79.9: 15.43
+	Hs
		271444 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZN624_HUMAN (729-1016): 7.57e-09: 63.7: 7.27