HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: H15 (P16401)
Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3)
Gene: H1-5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 25349213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006334 - nucleosome assembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 226
+	Hs
		417905 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H13_HUMAN (1-184): 1.62e-22: 93.3: 68.48
+	Hs
		417906 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H12_HUMAN (32-174): 1.09e-17: 80.2: 75.17
+	Hs
		417877 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H14_HUMAN (1-118): 3.82e-17: 78.6: 87.29
+	Hs
		418187 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H11_HUMAN (1-186): 2.89e-15: 73.6: 61.29
+	Hs
		271259 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		H1T_HUMAN (1-214): 6.06e-27: 104: 50.00