Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: CTCF (P49711)
Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)
Gene: CTCF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.714

The method score is based on:

Property Details
Experiments 19450526, 30459231, 14759373, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0008285 - negative regulation of cell population proliferation
GO:0045893 - positive regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 294
Hs

1 727
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024