HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20701745
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 538
+	Hs
		134827 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		131368 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91
+	Hs
		418065 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		131352 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91