HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.743

Property	Details
Experiments	26527279, 29568061, 25349213, 34079125, 16107701, 18259216, 20080577
Identification Methods	biochemical, affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	association, physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0016020 - membrane GO:0032991 - protein-containing complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 136
+	Hs
		418320 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		418366 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H3C_HUMAN (1-136): 5.49e-58: 177: 93.38
+	Hs
		418044 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		271347 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		H32_HUMAN (1-136): 6.5e-61: 185: 99.27