HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	20208519
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006281 - DNA repair
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 1992
+	Hs
		125090 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		WWP2_HUMAN (1053-1990): 0: 603: 18.31
+	Hs
		418643 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		WWP1_HUMAN (1038-1990): 0: 580: 16.88
+	Hs
		131368 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73
+	Hs
		134827 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IMA3_HUMAN (365-866): 1.41e-154: 488: 13.33
+	Hs
		418784 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52
+	Hs
		131352 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73
+	Hs
		418412 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72