HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: HOOK2 (Q96ED9)
Protein Hook homolog 2 (h-hook2) (hHK2)
Gene: HOOK2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21516116
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 719
+	Hs
		418895 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYH9_HUMAN (347-719): 2.16e-16: 85.9: 10.72
+	Hs
		451201 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MYH9_HUMAN (347-719): 2.16e-16: 85.9: 10.72
+	Dm
		419108 TPM1_DROME (2-282): 8.67e-51: 171: 45.97		MYSN_DROME (171-660): 1.62e-10: 66.9: 15.39
+	Hs
		451288 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		DLG5_HUMAN (187-645): 1.59e-15: 83: 16.84
+	Hs
		419054 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYO5C_HUMAN (162-651): 1.38e-13: 76.9: 16.44
+	Hs
		434354 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYH9_HUMAN (347-719): 2.16e-16: 85.9: 10.72
+	Hs
		418996 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		HOOK3_HUMAN (240-711): 2.67e-12: 72.4: 15.04
+	Hs
		434437 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYO5C_HUMAN (162-651): 1.38e-13: 76.9: 16.44
+	Hs
		724765 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MYH9_HUMAN (347-719): 2.16e-16: 85.9: 10.72
+	Dm
		828653 TPM4_DROME (58-285): 6.75e-09: 58.4: 17.54		Q8SX64_DROME (10-715): 9.81e-36: 147: 18.15
+	Dm
		404216 TPM2_DROME (2-284): 6.48e-36: 131: 47.70		MYSA_DROME (301-718): 7.36e-09: 61.4: 10.29
+	Hs
		110796 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MYH9_HUMAN (347-719): 2.16e-16: 85.9: 10.72
+	Hs
		1137917 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MRCKA_HUMAN (422-703): 3.89e-10: 65.8: 13.29
+	Rn
		222476 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKA_RAT (436-703): 2e-09: 63.5: 14.92
+	Rn
		1186812 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKB_RAT (77-446): 9.38e-09: 61.1: 14.36