HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 1893
+	Dm
		419108 TPM1_DROME (2-282): 8.67e-51: 171: 45.97		MYSN_DROME (161-1048): 2.84e-21: 104: 12.85
+	Hs
		418895 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		451201 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		434354 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		419054 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYO5C_HUMAN (103-604): 2.19e-16: 88: 18.67
+	Hs
		724765 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		419011 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Hs
		451293 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Hs
		148289 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		434437 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYO5C_HUMAN (103-604): 2.19e-16: 88: 18.67
+	Hs
		434415 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Hs
		932031 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Hs
		148661 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		1137917 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MRCKA_HUMAN (51-491): 8.55e-24: 112: 14.26
+	Rn
		222476 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKA_RAT (11-477): 1.06e-22: 108: 16.27
+	Hs
		110796 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		1268126 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Hs
		110802 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Rn
		1186812 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKB_RAT (63-534): 1.57e-09: 65.6: 17.47