Interactor 1: RHO1 (P06780)
GTP-binding protein RHO1 (EC 3.6.5.2) (Rho-type GTPase 1)
Gene: RHO1

Interactor 2: LRG1 (P35688)
Rho-GTPase-activating protein LRG1 (LIM-RhoGAP protein 1)
Gene: LRG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.916

The method score is based on:

Property Details
Experiments 11713681, 11447600, 23878277, 15514049, 26728856
Identification Methods two hybrid, protein complementation assay, enzymatic study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RhoGAP
Common GO terms GO:0000131 - incipient cellular bud site
GO:0005739 - mitochondrion
GO:0005934 - cellular bud tip
GO:0005935 - cellular bud neck
GO:0007165 - signal transduction
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 209
Sc

1 1017
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024