HitPredict

Interactor 1: SNF1 (P06782)
Carbon catabolite-derepressing protein kinase (EC 2.7.11.1) (Sucrose nonfermentating protein 1)
Gene: SNF1

Interactor 2: SIP2 (P34164)
SNF1 protein kinase subunit beta-2 (Protein SPM2) (SNF1-interacting protein 2)
Gene: SIP2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 1496382, 10688190, 7813428, 9121458, 17851534, 11805826, 11805837, 16429126, 18719252, 20489023, 21906795, 15719021, 16554755, 16319894, 27592031, 36147951, 37968396, 20529674
Identification Methods two hybrid, coimmunoprecipitation, affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation, enzymatic study
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AMPK1_CBM~AdenylateSensor, AMPKBI~AdenylateSensor, AMPK1_CBM~Pkinase, AMPKBI~Pkinase
Common GO terms GO:0001403 - invasive growth in response to glucose limitation
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0030447 - filamentous growth
GO:0031588 - nucleotide-activated protein kinase complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 633
Sc

1 415
+ Sc
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Ce
+ Ce
+ Rn
+ Hs
+ Sp
+ At
+ At
+ Zm
+ At
+ At
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024